Edda Kloppmann

Email:     kloppmann'at'rostlab.org

Research Interests
  • Structure and function of biological (macro-)molecules, in particular of proteins
  • Thermodynamics and statistical mechanics of biological systems
  • Simulation of molecular and macromolecular systems using classical methods
  • Membrane proteins, proton pumps, (archaeal) rhodopsins
  • Ligand binding, protonation states and probabilities, absorption/opsin shift
  • Methods: (Metropolis) Monte Carlo, dead-end elimination (DEE), X-DEE (extended DEE), molecular dynamics, continuum electrostatics, Poisson-Boltzmann electrostatics, Normal Mode Analysis, DFT


[1] E. Kloppmann, T. Becker and G. M. Ullmann. Electrostatic potential at the retinal of three archaeal rhodopsins: implications for their different absorption spectra. Proteins 61:953-965 (2005). [pdf]
[2] E. Kloppmann, G. M. Ullmann and T. Becker. An extended dead-end elimination algorithm to determine gap-free lists of low energy states. J. Comput. Chem. 28:2325-2335 (2007). [pdf]
[3] G. M. Ullmann, E. Kloppmann, T. Essigke, E.-M. Krammer, A. R. Klingen, T. Becker and E. Bombarda. Investigating the mechanisms of photosynthetic proteins using continuum electrostatics. Photosynth. Res. 97:33-53 (2008). [pdf]
[4] E. Kloppmann. Structure-function relationship of archaeal rhodopsin proteins analyzed by continuum electrostatics. PhD Thesis, Faculty of Biology, Chemistry and Earth Science, University of Bayreuth (2010). [pdf]

Curriculum Vitae

since 01/2011 Postdoc in the Bioinformatics and Computational Biology group of Prof. Dr. Burkhard Rost, TU Munich, Germany
05/2010 Dr. rer. nat. (PhD), University of Bayreuth, Germany, 1. Referee: Prof. Dr. G. Matthias Ullmann, 2. Referee: Prof. Dr. Franz X. Schmid
12/2003 - 04/2007 PhD student in the Computational Biochemistry/Bioinformatics group of Prof. Dr. G. Matthias Ullmann, University of Bayreuth, Germany
11/2002 - 11/2003 PhD student in the Computational Molecular Biophysics group of Prof. Dr. Jeremy C. Smith, IWR Heidelberg, Germany, Supervisor: Dr. G. Matthias Ullmann
02/2002 - 08/2002 Master thesis in the Computational Molecular Biophysics group of Prof. Dr. Jeremy C. Smith, IWR, Heidelberg, Germany
10/2000 - 09/2002 MSc in Molecular and Cellular Biology, University of Heidelberg, Germany
10/1997 - 09/2000 Studies in biology, chemistry and physics, University of Rostock, Germany